Emerging from the Shadow of Hemagglutinin: Neuraminidase Is an Important Target for Influenza Vaccination

Florian Krammer; Lei Li; Patrick C. Wilson

doi:10.1016/j.chom.2019.11.006

Emerging from the Shadow of Hemagglutinin: Neuraminidase Is an Important Target for Influenza Vaccination

Florian Krammer
, Lei Li
, Patrick C. Wilson

Research output: Contribution to journal › Comment/debate

14 Scopus citations

Abstract

Gilchuk et al. (2019) and Zhu et al. (2019) provide detailed structural information about epitopes on influenza virus N9 neuraminidase and characterize breadth, potency, mechanism of action, and in vivo protective effects of human antibodies targeting these epitopes. The findings highlight the importance of neuraminidase as a target for improved influenza virus vaccines.

Original language	English
Pages (from-to)	712-713
Number of pages	2
Journal	Cell Host and Microbe
Volume	26
Issue number	6
DOIs	https://doi.org/10.1016/j.chom.2019.11.006
State	Published - 11 Dec 2019

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10.1016/j.chom.2019.11.006

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title = "Emerging from the Shadow of Hemagglutinin: Neuraminidase Is an Important Target for Influenza Vaccination",

abstract = "Gilchuk et al. (2019) and Zhu et al. (2019) provide detailed structural information about epitopes on influenza virus N9 neuraminidase and characterize breadth, potency, mechanism of action, and in vivo protective effects of human antibodies targeting these epitopes. The findings highlight the importance of neuraminidase as a target for improved influenza virus vaccines.",

author = "Florian Krammer and Lei Li and Wilson, \{Patrick C.\}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

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T1 - Emerging from the Shadow of Hemagglutinin

T2 - Neuraminidase Is an Important Target for Influenza Vaccination

AU - Krammer, Florian

AU - Li, Lei

AU - Wilson, Patrick C.

PY - 2019/12/11

Y1 - 2019/12/11

N2 - Gilchuk et al. (2019) and Zhu et al. (2019) provide detailed structural information about epitopes on influenza virus N9 neuraminidase and characterize breadth, potency, mechanism of action, and in vivo protective effects of human antibodies targeting these epitopes. The findings highlight the importance of neuraminidase as a target for improved influenza virus vaccines.

AB - Gilchuk et al. (2019) and Zhu et al. (2019) provide detailed structural information about epitopes on influenza virus N9 neuraminidase and characterize breadth, potency, mechanism of action, and in vivo protective effects of human antibodies targeting these epitopes. The findings highlight the importance of neuraminidase as a target for improved influenza virus vaccines.

UR - https://www.scopus.com/pages/publications/85075949736

U2 - 10.1016/j.chom.2019.11.006

DO - 10.1016/j.chom.2019.11.006

M3 - Comment/debate

C2 - 31951584

AN - SCOPUS:85075949736

SN - 1931-3128

VL - 26

SP - 712

EP - 713

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 6

ER -

Emerging from the Shadow of Hemagglutinin: Neuraminidase Is an Important Target for Influenza Vaccination

Abstract

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