Emergency neurological life support: Status epilepticus

Jan Claassen, Robert Silbergleit, Scott D. Weingart, Wade S. Smith

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Patients with prolonged or rapidly recurring convulsions lasting more than 5 min are in status epilepticus (SE) and require immediate resuscitation. Although there are relatively few randomized clinical trials, available evidence and experience suggest that early and aggressive treatment of SE improves patient outcomes, forwhich reason it was chosen as an Emergency Neurologic Life Support protocol. The current approach to the emergency treatment of SE emphasizes rapid initiation of adequate doses of first line therapy, as well as accelerated second line anticonvulsant drugs and induced coma when these fail, coupled with admission to a unit capable of neurologic critical care and electroencephalography monitoring. This protocol not only will focus on the initial treatment of SE but also review subsequent steps in the protocol once the patient is hospitalized.

Original languageEnglish
Pages (from-to)S73-S78
JournalNeurocritical Care
Issue numberSUPPL. 1
StatePublished - Sep 2012


  • Anticonvulsant
  • EEG monitoring
  • Pharmacological coma
  • Protocol
  • Seizures


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