Efficient expression of HIV in immunocompetent mouse brain reveals a novel nonneurotoxic viral function in hippocampal synaptodendritic injury and memory impairment

Keyphrases

• Mouse Brain 100%
• Memory Impairment 100%
• Immunodeficient Mice 100%
• Efficient Expression 100%
• Synaptodendritic Injury 100%
• Viral Function 100%
• Antiretroviral Therapy 50%
• Neurotoxicity 50%
• Monocytic Cells 50%
• Dementia 33%
• Neurodegeneration 33%
• Neuronal Loss 33%
• EcoHIV 33%
• Cognitive Impairment 16%
• HIV Infection 16%
• HIV Patients 16%
• Hippocampus 16%
• HIV-related 16%
• Long-term Potentiation 16%
• Neuronal Dysfunction 16%
• Murine Leukemia Virus 16%
• Viral Proteins 16%
• Mild Cognitive Impairment 16%
• Disease Treatment 16%
• Brain Tissue 16%
• AIDS Patients 16%
• Neuronal Function 16%
• Insults 16%
• Associative Memory 16%
• Brain Abnormalities 16%
• Inflammatory Factors 16%
• Window of Opportunity 16%
• Arbor 16%
• TUNEL Assay 16%
• Histological Observation 16%
• Protein Factor 16%
• Hippocampal Slice 16%
• Neuroinflammatory Response 16%
• Microtubule-associated Protein 2 (MAP2) 16%
• Protein Quantification 16%
• Neuron-specific nuclear Protein 16%
• Virologically Suppressed Patients 16%
• Brain Memory 16%
• HIV Burden 16%
• Brain Infection 16%
• Synapsin 16%
• Hippocampal Dysfunction 16%
• Conventional Mouse 16%
• HIV Neuropathogenesis 16%
• Synaptodendritic 16%
• Cognitive Consequences 16%
• Intracerebral Infection 16%
• Spatial Working Memory 16%

Neuroscience

• Memory Disorder 100%
• Human Immunodeficiency Virus 100%
• Mouse Brain 100%
• Neurotoxicity 21%
• Neurodegeneration 14%
• Hippocampus 7%
• Long-Term Potentiation 7%
• Mild Cognitive Impairment 7%
• Staining Technique 7%
• TUNEL Assay 7%
• Synapsin II 7%
• Viral Protein 7%
• Associative Memory 7%
• Brain Abnormalities 7%
• Microtubule Associated Protein 2 7%
• Neuron Specific Nuclear Protein 7%
• Working Memory 7%