Effects of propantheline bromide on basal growth hormone, cortisol and prolactin levels

Bonnie M. Davis; Aleksander A. Mathé; Richard C. Mohs; Michael I. Levy; Kenneth L. Davis

doi:10.1016/0306-4530(83)90046-X

Effects of propantheline bromide on basal growth hormone, cortisol and prolactin levels

Bonnie M. Davis, Aleksander A. Mathé, Richard C. Mohs, Michael I. Levy, Kenneth L. Davis

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Propantheline bromide, a peripheral anticholinergic drug with muscarinic and nicotinic blocking properties, was given by mouth to normal young men. Propantheline (45 mg) significantly lowered basal growth hormone concentrations at 0800 hr, 12 hr after administration. Propantheline (30 mg) tended (p = 0.08) to lower growth hormone concentrations at 1200 hr, 16 hr after administration. Cortisol and prolactin levels were not changed 12, 16 and 20 hr after propantheline (30 mg) nor 12 hr after propantheline (45 mg).

Original language	English
Pages (from-to)	103-107
Number of pages	5
Journal	Psychoneuroendocrinology
Volume	8
Issue number	1
DOIs	https://doi.org/10.1016/0306-4530(83)90046-X
State	Published - 1983

Keywords

Acetylcholine
anticholinergic
cortisol
growth hormone
muscarinic
nicotinic
prolactin
propantheline

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title = "Effects of propantheline bromide on basal growth hormone, cortisol and prolactin levels",

abstract = "Propantheline bromide, a peripheral anticholinergic drug with muscarinic and nicotinic blocking properties, was given by mouth to normal young men. Propantheline (45 mg) significantly lowered basal growth hormone concentrations at 0800 hr, 12 hr after administration. Propantheline (30 mg) tended (p = 0.08) to lower growth hormone concentrations at 1200 hr, 16 hr after administration. Cortisol and prolactin levels were not changed 12, 16 and 20 hr after propantheline (30 mg) nor 12 hr after propantheline (45 mg).",

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AU - Davis, Bonnie M.

AU - Mathé, Aleksander A.

AU - Mohs, Richard C.

AU - Levy, Michael I.

AU - Davis, Kenneth L.

PY - 1983

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N2 - Propantheline bromide, a peripheral anticholinergic drug with muscarinic and nicotinic blocking properties, was given by mouth to normal young men. Propantheline (45 mg) significantly lowered basal growth hormone concentrations at 0800 hr, 12 hr after administration. Propantheline (30 mg) tended (p = 0.08) to lower growth hormone concentrations at 1200 hr, 16 hr after administration. Cortisol and prolactin levels were not changed 12, 16 and 20 hr after propantheline (30 mg) nor 12 hr after propantheline (45 mg).

AB - Propantheline bromide, a peripheral anticholinergic drug with muscarinic and nicotinic blocking properties, was given by mouth to normal young men. Propantheline (45 mg) significantly lowered basal growth hormone concentrations at 0800 hr, 12 hr after administration. Propantheline (30 mg) tended (p = 0.08) to lower growth hormone concentrations at 1200 hr, 16 hr after administration. Cortisol and prolactin levels were not changed 12, 16 and 20 hr after propantheline (30 mg) nor 12 hr after propantheline (45 mg).

KW - Acetylcholine

KW - anticholinergic

KW - cortisol

KW - growth hormone

KW - muscarinic

KW - nicotinic

KW - prolactin

KW - propantheline

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JO - Psychoneuroendocrinology

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ER -

Effects of propantheline bromide on basal growth hormone, cortisol and prolactin levels

Abstract

Keywords

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