Effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on exogenous and oxidative DNA damage (EXPAH project): Description of the population under study

Emanuela Taioli; Radim J. Sram; Seymour Garte; Ivan Kalina; Todor A. Popov; Peter B. Farmer

doi:10.1016/j.mrfmmm.2007.02.016

Effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on exogenous and oxidative DNA damage (EXPAH project): Description of the population under study

Emanuela Taioli, Radim J. Sram, Seymour Garte, Ivan Kalina, Todor A. Popov, Peter B. Farmer

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

The EXPAH project was a molecular epidemiology study whose aims were to evaluate the hypothesis that polycyclic aromatic hydrocarbons (PAHs) are a major source of genotoxic activities of organic mixtures associated with air pollution. Biomarkers of exposure, effects and susceptibility, and oxidative DNA damage were measured in three PAH-exposed populations from Prague (Czech Republic), Kosice (Slovakia) and Sofia (Bulgaria). Control populations were included from each city. In total 356 individuals were enrolled. A questionnaire was used to determine life style/dietary factors. Ambient air exposure was measured by stationary monitoring, and personal exposure monitoring was also carried out. The characteristics of the population are described in this paper together with their personal exposure to carcinogenic PAHs (c-PAHs). The dose of c-PAH exposure was found to vary between the occupationally exposed (e.g. policemen and bus drivers) and the control populations in each country, and also varied from country to country.

Original language	English
Pages (from-to)	1-6
Number of pages	6
Journal	Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volume	620
Issue number	1-2
DOIs	https://doi.org/10.1016/j.mrfmmm.2007.02.016
State	Published - 1 Jul 2007
Externally published	Yes

Keywords

Molecular epidemiology
PAH-exposed populations
c-PAH

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10.1016/j.mrfmmm.2007.02.016

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Taioli, E., Sram, R. J., Garte, S., Kalina, I., Popov, T. A., & Farmer, P. B. (2007). Effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on exogenous and oxidative DNA damage (EXPAH project): Description of the population under study. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 620(1-2), 1-6. https://doi.org/10.1016/j.mrfmmm.2007.02.016

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title = "Effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on exogenous and oxidative DNA damage (EXPAH project): Description of the population under study",

abstract = "The EXPAH project was a molecular epidemiology study whose aims were to evaluate the hypothesis that polycyclic aromatic hydrocarbons (PAHs) are a major source of genotoxic activities of organic mixtures associated with air pollution. Biomarkers of exposure, effects and susceptibility, and oxidative DNA damage were measured in three PAH-exposed populations from Prague (Czech Republic), Kosice (Slovakia) and Sofia (Bulgaria). Control populations were included from each city. In total 356 individuals were enrolled. A questionnaire was used to determine life style/dietary factors. Ambient air exposure was measured by stationary monitoring, and personal exposure monitoring was also carried out. The characteristics of the population are described in this paper together with their personal exposure to carcinogenic PAHs (c-PAHs). The dose of c-PAH exposure was found to vary between the occupationally exposed (e.g. policemen and bus drivers) and the control populations in each country, and also varied from country to country.",

keywords = "Molecular epidemiology, PAH-exposed populations, c-PAH",

author = "Emanuela Taioli and Sram, {Radim J.} and Seymour Garte and Ivan Kalina and Popov, {Todor A.} and Farmer, {Peter B.}",

note = "Funding Information: The authors acknowledge the European Commission {\textquoteleft}Quality of life and management of living resources{\textquoteright} programme (QLK4-CT-2000-00091) for financial support. Ms K. Lyubomirova is acknowledged for assistance with data collection.",

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Taioli, E, Sram, RJ, Garte, S, Kalina, I, Popov, TA & Farmer, PB 2007, 'Effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on exogenous and oxidative DNA damage (EXPAH project): Description of the population under study', Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, vol. 620, no. 1-2, pp. 1-6. https://doi.org/10.1016/j.mrfmmm.2007.02.016

Effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on exogenous and oxidative DNA damage (EXPAH project): Description of the population under study. / Taioli, Emanuela; Sram, Radim J.; Garte, Seymour et al.
In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, Vol. 620, No. 1-2, 01.07.2007, p. 1-6.

Research output: Contribution to journal › Article › peer-review

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AU - Taioli, Emanuela

AU - Sram, Radim J.

AU - Garte, Seymour

AU - Kalina, Ivan

AU - Popov, Todor A.

AU - Farmer, Peter B.

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Effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on exogenous and oxidative DNA damage (EXPAH project): Description of the population under study

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Keywords

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