Effects of hydration on blood rheology

George A. Vlastos, Christine C. Tangney, Robert S. Rosenson

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

This study investigated the impact of oral fluid intake on blood rheology of 17 healthy adults following a 12-14 hour overnight fast from food and drink. An oral fluid load of 500 ml was consumed every 30 minutes for 2 hours. Blood viscosity values at shear rates of 1, 10 and 100 s-1 were reduced (p < 0.05 to p < 0.01) at 30 and 120 minutes following hydration; however, these differences were not significant after hematocrit correction. With fluid intake, both uncorrected and corrected viscous component of blood viscoelasticity at oscillatory shear rate of 1 s-1 and at a constant frequency of 2 Hz were reduced (p < 0.05 to p < 0.001) at all time points as compared to fasting values. The corrected elastic component of blood viscoelasticity increased 90 minutes after hydration (p < 0.05). An overnight fast is accompanied by rheological abnormalities that are altered by fluid intake.

Original languageEnglish
Pages (from-to)41-49
Number of pages9
JournalClinical Hemorheology and Microcirculation
Volume28
Issue number1
StatePublished - 2003
Externally publishedYes

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