Effects of dopaminergic and subthalamic stimulation on musical performance

Floris T. Van Vugt; Michael Schüpbach; Eckart Altenmüller; Eric Bardinet; Jérôme Yelnik; Thomas D. Hälbig

doi:10.1007/s00702-012-0923-7

Effects of dopaminergic and subthalamic stimulation on musical performance

Floris T. Van Vugt, Michael Schüpbach, Eckart Altenmüller, Eric Bardinet, Jérôme Yelnik, Thomas D. Hälbig

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Although subthalamic-deep brain stimulation (STN-DBS) is an efficient treatment for Parkinson's disease (PD), its effects on fine motor functions are not clear. We present the case of a professional violinist with PD treated with STN-DBS. DBS improved musical articulation, intonation and emotional expression and worsened timing relative to a timekeeper (metronome). The same effects were found for dopaminergic treatment. These results suggest that STN-DBS, mimicking the effects of dopaminergic stimulation, improves fine-tuned motor behaviour whilst impairing timing precision.

Original language	English
Pages (from-to)	755-759
Number of pages	5
Journal	Journal of Neural Transmission
Volume	120
Issue number	5
DOIs	https://doi.org/10.1007/s00702-012-0923-7
State	Published - May 2013

Keywords

Deep brain stimulation
Dopamine
Motor control
Musical performance
Parkinson's disease
Subthalamic nucleus

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10.1007/s00702-012-0923-7

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abstract = "Although subthalamic-deep brain stimulation (STN-DBS) is an efficient treatment for Parkinson's disease (PD), its effects on fine motor functions are not clear. We present the case of a professional violinist with PD treated with STN-DBS. DBS improved musical articulation, intonation and emotional expression and worsened timing relative to a timekeeper (metronome). The same effects were found for dopaminergic treatment. These results suggest that STN-DBS, mimicking the effects of dopaminergic stimulation, improves fine-tuned motor behaviour whilst impairing timing precision.",

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AU - Altenmüller, Eckart

AU - Bardinet, Eric

AU - Yelnik, Jérôme

AU - Hälbig, Thomas D.

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N2 - Although subthalamic-deep brain stimulation (STN-DBS) is an efficient treatment for Parkinson's disease (PD), its effects on fine motor functions are not clear. We present the case of a professional violinist with PD treated with STN-DBS. DBS improved musical articulation, intonation and emotional expression and worsened timing relative to a timekeeper (metronome). The same effects were found for dopaminergic treatment. These results suggest that STN-DBS, mimicking the effects of dopaminergic stimulation, improves fine-tuned motor behaviour whilst impairing timing precision.

AB - Although subthalamic-deep brain stimulation (STN-DBS) is an efficient treatment for Parkinson's disease (PD), its effects on fine motor functions are not clear. We present the case of a professional violinist with PD treated with STN-DBS. DBS improved musical articulation, intonation and emotional expression and worsened timing relative to a timekeeper (metronome). The same effects were found for dopaminergic treatment. These results suggest that STN-DBS, mimicking the effects of dopaminergic stimulation, improves fine-tuned motor behaviour whilst impairing timing precision.

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KW - Dopamine

KW - Motor control

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Effects of dopaminergic and subthalamic stimulation on musical performance

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Keywords

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