@article{04656b00e69c4efa8a6aacbe85a43b2e,
title = "Effect of tumor promoters on human T cell leukemia/lymphoma virus (HTLV)-structural protein induction in adult T-cell leukemia cells",
abstract = "We assayed the capacity of tumor promoters to induce human T-cell leukemia/lymphoma virus (HTLV) structural proteins p19 and p24 from the HTLV genome-carrying adult T-cell leukemia (ATL) cell lines, MT-1 and KH-2lo, and fresh ATL cells. Among the tested substances, 12-O-tetradecanoyl phorbol-13-acetate (TPA), 12-hexadecanoyl-phorbol-13-acetate (HPA) and teleocidin induced HTLV structural protein p19 and p24. This suggests that certain environmental substances, especially those known to be tumor promoters, may activate the HTLV-gene in ATL cells.",
author = "Yoshinobu Nakao and Shuichi Matsuda and Toshimitsu Matsui and Toshitaro Nakagawa and Takuo Fujita and Takashi Uchiyama and Sakan Maeda and Yuruko Okamoto and Tohru Masaoka and Yohei Ito",
note = "Funding Information: We are most grateful to Dr. Robert C. Gallo (National Cancer Institute, NIH, Bethesda, MD) for generously providing anti-ATLV p19 and p24 antibodies. We also thank Dr. I. Miyoshi (Department of Medicine, Kochi Medical College, Nangokucity, Japan) for providing MT-1 cells and Mr. D. Mrozek for his critical reading of the manuscript. This work was supported in part by a Grant-in-Aid for Cancer Research from the Ministry of Education, Science and Culture of Japan and a grant from the Hyogo Prefectural Cancer Society.",
year = "1984",
month = sep,
doi = "10.1016/0304-3835(84)90128-9",
language = "English",
volume = "24",
pages = "129--139",
journal = "Cancer Letters",
issn = "0304-3835",
publisher = "Elsevier Ireland Ltd",
number = "2",
}