Abstract
Serum sialic acid levels were determined in 66 patients of carcinoma cervix and 25 control women matched for age. Mean sialic acid level was significantly elevated (p < 0.001) in cancer cervix patients as compared to controls. Patients were treated with 50-65 Gy of radiation in 5-6.5 weeks, Post-therapy levels were again determined. Radiotherapy caused decline in serum sialic acid level in all the patients except one. Mean post-therapy level was significantly lower as compared to pretreatment level (p < 0.001). It was also observed that fall in sialic acid level was significantly higher (p < 0.05) in early stage patients as compared to late stage. No relationship was observed in the dose of radiation and fall in serum sialic acid level. A significantly higher fall in serum sialic acid level was observed in patients having complete clinical response as compared to partial or non-responders to radiation treatment (p < 0.001).
| Original language | English |
|---|---|
| Pages (from-to) | 56-58 |
| Number of pages | 3 |
| Journal | Indian Journal of Clinical Biochemistry |
| Volume | 11 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1996 |
| Externally published | Yes |
Keywords
- Carcinoma cervix
- Radiotherapy
- Serum sialic acid