Effect of mitomycin C and hydroxyurea on the expression of the epstein-barr virus cycle following P3HR-1 superinfection

M. H. Moar, G. Klein

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Epstein-Barr virus (EBV) DNA synthesis following EBV P3HR-1 superinfection of the Burkitt lymphoma cell line, Daudi, is refractory to mitomycin C and hydroxyurea at concentrations which inhibit cell DNA synthesis to greater than 98% of control values. Further, neither mitomycin C nor hydroxyurea inhibit virus antigen synthesis following P3HR-1 superinfection.

Original languageEnglish
Pages (from-to)178-185
Number of pages8
JournalIntervirology
Volume13
Issue number3
DOIs
StatePublished - 1980
Externally publishedYes

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