Effect of exposure duration and light spectra on nighttime melatonin suppression in adolescents and adults

R. Nagare, B. Plitnick, M. G. Figueiro

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

This study investigated how light exposure duration affects melatonin suppression, a well-established marker of circadian phase, and whether adolescents (13–18 years) are more sensitive to short-wavelength (blue) light than adults (32–51 years). Twenty-four participants (12 adolescents, 12 adults) were exposed to three lighting conditions during successive 4-h study nights that were separated by at least one week. In addition to a dim light (<5 lux) control, participants were exposed to two light spectra (warm (2700 K) and cool (5600 K)) delivering a circadian stimulus of 0.25 at eye level. Repeated measures analysis of variance revealed a significant main effect of exposure duration, indicating that a longer duration exposure suppressed melatonin to a greater degree. The analysis further revealed a significant main effect of spectrum and a significant interaction between spectrum and participant age. For the adolescents, but not the adults, melatonin suppression was significantly greater after exposure to the 5600 K intervention (43%) compared to the 2700 K intervention (29%), suggesting an increased sensitivity to short-wavelength radiation. These results will be used to extend the model of human circadian phototransduction to incorporate factors such as exposure duration and participant age to better predict effective circadian stimulus.

Original languageEnglish
Pages (from-to)530-543
Number of pages14
JournalLighting Research and Technology
Volume51
Issue number4
DOIs
StatePublished - 1 Jun 2019
Externally publishedYes

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