Effect of diclofenac sodium and bandage contact lens following photorefractive keratectomy on ocular response to light and postoperative comfort

Purpose. To evaluate the effect of diclofenac sodium drops and bandage contact lens (BCL) following photorefractive keratectomy (PRK) on preoperative and postoperative ocular response to light and discomfort. Methods. Seventy-seven eyes of 62 patients undergoing PRK were randomly assigned to the following treatment groups: Group 1- pressure patch, no diclofenac; Group 2- pressure patch, diclofenac; Group 3- BCL; no diclofenac; Group 4- BCL, diclofenac. At baseline (preoperative), and postoperative day I, and day 3-4, patients were evaluated for ocular response to light by a calibrated light source, and the degree of self-reported discomfort by a modified McGill pain questionnaire. Results. At day 1, there was no difference in light sensitivity between all groups but on postoperative day 4, Groups 3 and 4 could tolerate more light than the other groups. Groups 2 and 4 experienced less postoperative discomfort at Day 1. The rate of reepitheliauzation was shorter in groups 3 and 4. Conclusions: BCL improves postoperative light sensitivity, discomfort, and reepithelialization rate. Diclofenac sodium drops reduces discomfort.