Effect of azidothymidine (AZT) on P24 antigen levels in patients with AIDS‐related complex and AIDS

Mohan M. Reddy, George McKinley, Arthur Englard, Michael H. Grieco

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Circulating HIV P24 antigen levels at baseline and following AZT therapy were measured in 9 patients with ARC and 11 patients with AIDS. Eight of these patients had no detectable levels of P24. The P24 antigen levels in the remaining 12 patients decreased significantly after AZT treatment. Following discontinuation of AZT treatment in 2 patients, the P24 antigen levels went up. These results clearly demonstrate the efficacy of AZT in reducing P24 antigen levels in circulation.

Original languageEnglish
Pages (from-to)199-201
Number of pages3
JournalJournal of Clinical Laboratory Analysis
Volume3
Issue number4
DOIs
StatePublished - 1989
Externally publishedYes

Keywords

  • AIDS‐related complex
  • HIV P24 antigen
  • acquired immune deficiency syndrome (AIDS)
  • azidothymidine (AZT)
  • therapy

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