Eating disorders and obesity: bridging clinical, neurobiological, and therapeutic perspectives

Lucia Camacho-Barcia, Katrin Elisabeth Giel, Susana Jiménez-Murcia, Julio Álvarez Pitti, Nadia Micali, Ignacio Lucas, Romina Miranda-Olivos, Lucero Munguia, Manuel Tena-Sempere, Stephan Zipfel, Fernando Fernández-Aranda

Research output: Contribution to journalReview articlepeer-review

Abstract

Eating disorders (EDs) and obesity are complex health conditions sharing various risk and maintenance factors, intensified in cases of comorbidity. This review explores the similarities and connections between these conditions, examining different facets from a multidisciplinary perspective, among them comorbidities, metabolic and psychological factors, neurobiological aspects, and management and therapy implications. We aim to investigate the common characteristics and complexities of weight and EDs and explore their interrelationships in individuals who experience both. The rising prevalence of EDs in people with obesity necessitates integrated approaches to study this comorbidity and to identify and analyze both common and distinct features of these conditions. This review may offer new opportunities for simultaneous prevention and management approaches, as well as future lines of research.

Original languageEnglish
Pages (from-to)361-379
Number of pages19
JournalTrends in Molecular Medicine
Volume30
Issue number4
DOIs
StatePublished - Apr 2024
Externally publishedYes

Keywords

  • binge eating
  • eating disorders
  • neurobiology
  • obesity
  • treatment

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