Early response to clozapine in schizophrenia

Robert G. Stern, René S. Kahn, Michael Davidson, Rena M. Nora, Kenneth L. Davis

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


Forty schizophrenic patients were treated with clozapine for 5 weeks. Patients were then classified as treatment responders or nonresponders according to a priori established criteria. After only 1 week of treatment, the responders showed a significant decrease on the Brief Psychiatric Rating Scale (BPRS) total score and the psychosis and tension subscale scores. Higher BPRS scores at baseline and larger improvements in BPRS scores after the first week predicted a more favorable outcome in this trial and yielded good classification accuracy.

Original languageEnglish
Pages (from-to)1817-1818
Number of pages2
JournalAmerican Journal of Psychiatry
Issue number12
StatePublished - Dec 1994


Dive into the research topics of 'Early response to clozapine in schizophrenia'. Together they form a unique fingerprint.

Cite this