Early Lung Cancer Action Project: Annual screening using single-slice helical CT

Claudia I. Henschke, David F. Yankelevitz, Daniel M. Libby, Dorothy McCauley, Mark Pasmantier, Nasser K. Altorki, James P. Smith, Olli S. Miettinen

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

The advent of helical CT imaging held promise for the early diagnosis, and thereby, for enhanced curability of lung cancer - a highly fatal disease. In 1993, the Early Lung Cancer Action Project (ELCAP) was initiated and experimentally screened a cohort of 1,000 high-risk persons. Here we summarize the results of the baseline and annual repeat CT screening of these 1,000 subjects. CT-based screening (compared to traditional radiology) was clearly shown to enhance the detection of lung cancer at earlier and more curable stages. A discussion follows of the meaning of the results and possible future screening protocols.

Original languageEnglish
Pages (from-to)124-134
Number of pages11
JournalAnnals of the New York Academy of Sciences
Volume952
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • CT-imaging
  • Cancer screening protocols
  • Early Lung Cancer Action Project (ELCAP)
  • Lung cancer

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