TY - JOUR
T1 - Early Lung Cancer Action Project
T2 - Annual screening using single-slice helical CT
AU - Henschke, Claudia I.
AU - Yankelevitz, David F.
AU - Libby, Daniel M.
AU - McCauley, Dorothy
AU - Pasmantier, Mark
AU - Altorki, Nasser K.
AU - Smith, James P.
AU - Miettinen, Olli S.
PY - 2001
Y1 - 2001
N2 - The advent of helical CT imaging held promise for the early diagnosis, and thereby, for enhanced curability of lung cancer - a highly fatal disease. In 1993, the Early Lung Cancer Action Project (ELCAP) was initiated and experimentally screened a cohort of 1,000 high-risk persons. Here we summarize the results of the baseline and annual repeat CT screening of these 1,000 subjects. CT-based screening (compared to traditional radiology) was clearly shown to enhance the detection of lung cancer at earlier and more curable stages. A discussion follows of the meaning of the results and possible future screening protocols.
AB - The advent of helical CT imaging held promise for the early diagnosis, and thereby, for enhanced curability of lung cancer - a highly fatal disease. In 1993, the Early Lung Cancer Action Project (ELCAP) was initiated and experimentally screened a cohort of 1,000 high-risk persons. Here we summarize the results of the baseline and annual repeat CT screening of these 1,000 subjects. CT-based screening (compared to traditional radiology) was clearly shown to enhance the detection of lung cancer at earlier and more curable stages. A discussion follows of the meaning of the results and possible future screening protocols.
KW - CT-imaging
KW - Cancer screening protocols
KW - Early Lung Cancer Action Project (ELCAP)
KW - Lung cancer
UR - http://www.scopus.com/inward/record.url?scp=0035680449&partnerID=8YFLogxK
U2 - 10.1111/j.1749-6632.2001.tb02733.x
DO - 10.1111/j.1749-6632.2001.tb02733.x
M3 - Article
C2 - 11795431
AN - SCOPUS:0035680449
SN - 0077-8923
VL - 952
SP - 124
EP - 134
JO - Annals of the New York Academy of Sciences
JF - Annals of the New York Academy of Sciences
ER -