Early and Late Factors Impacting Patient and Graft Outcome in Pediatric Liver Transplantation: Summary of an ESPGHAN Monothematic Conference

Valérie A. McLin, Upton Allen, Olivia Boyer, John Bucuvalas, Michele Colledan, Maria Cristina Cuturi, Lorenzo D'Antiga, Dominique Debray, Antal Dezsofi, Jean De Ville De Goyet, Anil Dhawan, Ozlem Durmaz, Christine Falk, Sandy Feng, Björn Fischler, Stéphanie Franchi-Abella, Esteban Frauca, Rainer Ganschow, Stephen Gottschalk, Nedim HadzicLoreto Hierro, Simon Horslen, Stefan Hubscher, Vincent Karam, Deirdre Kelly, Britta Maecker-Kolhoff, George Mazariegos, Patrick McKiernan, Anette Melk, Valerio Nobili, Funda Ozgenç, Raymond Reding, Marco Sciveres, Khalid Sharif, Piotr Socha, Christian Toso, Pietro Vajro, Anita Verma, Barbara E. Wildhaber, Ulrich Baumann

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

As pediatric liver transplantation comes of age, experts gathered to discuss current paradigms and define gaps in knowledge warranting research to further improve patient and graft outcomes. Identified areas ripe for collaborative research include understanding the molecular and cellular mechanisms of tolerance and the role of donor-specific antibodies, considering ways to expand donor pool, minimizing long-term side effects of immunosuppression, and fine-tuning surgical techniques to minimize biliary and vascular complications.

Original languageEnglish
Pages (from-to)e53-e59
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume65
Issue number3
DOIs
StatePublished - 1 Sep 2017
Externally publishedYes

Keywords

  • complications
  • liver transplantation
  • pediatric
  • research goals
  • tolerance

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