TY - GEN
T1 - Dual SLO/T-scan based en face ultrahigh resolution OCT for ophthalmic imaging
AU - Cucu, Radu G.
AU - Podoleanu, Adrian Gh
AU - Pedro, Justin
AU - Rogers, John A.
AU - Rosen, Richard B.
AU - Van Velthoven, Mirjam
AU - Garcia, Patricia
AU - Shidlovski, Vladimir
PY - 2006
Y1 - 2006
N2 - We report a versatile imaging system combining scanning laser ophthalmoscopy (SLO) and T-scan based en face ultrahigh resolution optical coherence tomography (OCT). The image carrier is generated using the optical path difference modulation introduced by the X-Y galvo-scanner mirrors specific to en face OCT (without optical modulators in the reference arm). The light source is a compact superluminescent diode based source with 150 nm FWHM spectrum, centered at 890 nm. We demonstrate en face B-scan and C-scan ultrahigh resolution OCT imaging of the human retina in vivo, with an axial resolution of 3.2 μm in tissue. The system is capable of acquiring large lateral size ultrahigh resolution OCT scans of a maximum field size of 20°. The acquisition speed is up to 2 frames/s for both OCT B-scans and C-scans. The measured system sensitivity is more than 98 dB, for a power level to the target of 1 mW and maximum lateral scan size. The C-scans are, to the best of our knowledge, the first and the largest size reported ultrahigh resolution C-scans of the human retina in vivo. The instrument is assembled on a chin rest and ready to be used for clinical imaging. SLO and ultrahigh resolution OCT C-scans are acquired simultaneously and displayed side by side. This allows users in a clinical environment to correlate details of the same feature in the area of interest in both images and also choose precisely in the SLO image the location where to perform the ultrahigh resolution en face B-scan.
AB - We report a versatile imaging system combining scanning laser ophthalmoscopy (SLO) and T-scan based en face ultrahigh resolution optical coherence tomography (OCT). The image carrier is generated using the optical path difference modulation introduced by the X-Y galvo-scanner mirrors specific to en face OCT (without optical modulators in the reference arm). The light source is a compact superluminescent diode based source with 150 nm FWHM spectrum, centered at 890 nm. We demonstrate en face B-scan and C-scan ultrahigh resolution OCT imaging of the human retina in vivo, with an axial resolution of 3.2 μm in tissue. The system is capable of acquiring large lateral size ultrahigh resolution OCT scans of a maximum field size of 20°. The acquisition speed is up to 2 frames/s for both OCT B-scans and C-scans. The measured system sensitivity is more than 98 dB, for a power level to the target of 1 mW and maximum lateral scan size. The C-scans are, to the best of our knowledge, the first and the largest size reported ultrahigh resolution C-scans of the human retina in vivo. The instrument is assembled on a chin rest and ready to be used for clinical imaging. SLO and ultrahigh resolution OCT C-scans are acquired simultaneously and displayed side by side. This allows users in a clinical environment to correlate details of the same feature in the area of interest in both images and also choose precisely in the SLO image the location where to perform the ultrahigh resolution en face B-scan.
KW - Combined simultaneous SLO/OCT imaging
KW - T-scan
KW - Ultrahigh resolution OCT
KW - en face scanning
UR - http://www.scopus.com/inward/record.url?scp=33646266966&partnerID=8YFLogxK
U2 - 10.1117/12.649047
DO - 10.1117/12.649047
M3 - Conference contribution
AN - SCOPUS:33646266966
SN - 0819461210
SN - 9780819461216
T3 - Proceedings of SPIE - The International Society for Optical Engineering
BT - Proceedings of SPIE - The International Society for Optical Engineering
T2 - Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X
Y2 - 23 January 2006 through 25 January 2006
ER -