TY - JOUR
T1 - Drug-Resistant Tuberculosis
AU - Bonforte, Richard J.
AU - Gribetz, Irwin
PY - 1971/4/8
Y1 - 1971/4/8
N2 - The article, “Primary Drug-Resistant Tuberculosis” by Steiner et al. (N Engl J Med 283:1353–1358, 1970), should abolish any doubts that still exist about the ability of drug-resistant strains of Mycobacterium tuberculosis hominis to cause infection and progressive disease in human beings. It is known that children who have complicated pulmonary tuberculosis caused by infection with streptomycin-resistant tubercle bacilli and who have been treated only with streptomycin generally have a progressive downhill course.1 However, there has been considerable controversy over the role of isoniazid (INH)-resistant strains since the clinical course in patients infected with such strains and treated.
AB - The article, “Primary Drug-Resistant Tuberculosis” by Steiner et al. (N Engl J Med 283:1353–1358, 1970), should abolish any doubts that still exist about the ability of drug-resistant strains of Mycobacterium tuberculosis hominis to cause infection and progressive disease in human beings. It is known that children who have complicated pulmonary tuberculosis caused by infection with streptomycin-resistant tubercle bacilli and who have been treated only with streptomycin generally have a progressive downhill course.1 However, there has been considerable controversy over the role of isoniazid (INH)-resistant strains since the clinical course in patients infected with such strains and treated.
UR - http://www.scopus.com/inward/record.url?scp=0015214859&partnerID=8YFLogxK
U2 - 10.1056/NEJM197104082841425
DO - 10.1056/NEJM197104082841425
M3 - Letter
C2 - 4994047
AN - SCOPUS:0015214859
SN - 0028-4793
VL - 284
SP - 795
EP - 796
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 14
ER -