Drug Addiction: Mechanisms of Nicotine Dependence Unmasked by Gene Editing

William M. Howe; Paul J. Kenny

doi:10.1016/j.cub.2018.09.003

Drug Addiction: Mechanisms of Nicotine Dependence Unmasked by Gene Editing

William M. Howe, Paul J. Kenny

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

New gene editing technologies are enabling exploration of previously intractable features of genetic risk for drug addiction. A recent study using this technology reveals new insights into how a mutation linked to tobacco dependence influences the addictive properties of nicotine. New gene editing technologies are enabling exploration of previously intractable features of genetic risk for drug addiction. A recent study using this technology reveals new insights into how a mutation linked to tobacco dependence influences the addictive properties of nicotine.

Original language	English
Pages (from-to)	R1205-R1207
Journal	Current Biology
Volume	28
Issue number	20
DOIs	https://doi.org/10.1016/j.cub.2018.09.003
State	Published - 22 Oct 2018

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title = "Drug Addiction: Mechanisms of Nicotine Dependence Unmasked by Gene Editing",

abstract = "New gene editing technologies are enabling exploration of previously intractable features of genetic risk for drug addiction. A recent study using this technology reveals new insights into how a mutation linked to tobacco dependence influences the addictive properties of nicotine. New gene editing technologies are enabling exploration of previously intractable features of genetic risk for drug addiction. A recent study using this technology reveals new insights into how a mutation linked to tobacco dependence influences the addictive properties of nicotine.",

author = "Howe, {William M.} and Kenny, {Paul J.}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",

year = "2018",

month = oct,

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AU - Howe, William M.

AU - Kenny, Paul J.

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Y1 - 2018/10/22

N2 - New gene editing technologies are enabling exploration of previously intractable features of genetic risk for drug addiction. A recent study using this technology reveals new insights into how a mutation linked to tobacco dependence influences the addictive properties of nicotine. New gene editing technologies are enabling exploration of previously intractable features of genetic risk for drug addiction. A recent study using this technology reveals new insights into how a mutation linked to tobacco dependence influences the addictive properties of nicotine.

AB - New gene editing technologies are enabling exploration of previously intractable features of genetic risk for drug addiction. A recent study using this technology reveals new insights into how a mutation linked to tobacco dependence influences the addictive properties of nicotine. New gene editing technologies are enabling exploration of previously intractable features of genetic risk for drug addiction. A recent study using this technology reveals new insights into how a mutation linked to tobacco dependence influences the addictive properties of nicotine.

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DO - 10.1016/j.cub.2018.09.003

M3 - Short survey

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SN - 0960-9822

VL - 28

SP - R1205-R1207

JO - Current Biology

JF - Current Biology

IS - 20

ER -

Drug Addiction: Mechanisms of Nicotine Dependence Unmasked by Gene Editing

Abstract

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