Double-phase Tc-99m-sestamibi SPECT imaging in a case of glomus jugulare tumor

L. Kostakoglu, N. Elahi, D. Uzal, B. Khademi, L. Atahan, C. F. Bekdik

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6 Scopus citations


We performed a double-phase Tc-99m-Sestamibi SPECT study on a patient who presented with a mass located at the skull base. The results were compared with double-phase T1-201 SPECT study. Early phase (30 min) SPECT images of both radiopharmaceuticals demonstrated increased radiotracer uptake in the region of the tumor. However, late images (180 min) revealed rapid wash-out of Tc-99m-SestaMIBI from the tumor, suggestive of a benign vascular tumor, while T1-201 images showed slower wash-out. Tc-99m-SestaMIBI SPECT findings were also confirmed by carotid angiography and biopsy, while a contemporaneous MRI scan was inconclusive in differentiating benign from malignant tumor. Initial and one-year follow-up whole body CT scans were negative for any metastatic sites, supporting the diagnosis of benign glomus jugulare tumor.

Original languageEnglish
Pages (from-to)331-334
Number of pages4
JournalRadiation Medicine - Medical Imaging and Radiation Oncology
Issue number5
StatePublished - 1997
Externally publishedYes


  • Double-phase imaging
  • Glomus jugulare tumor
  • Paraganglioma
  • Tc-99m-sestamibi


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