Doppelgänger dilemma: Leiomyoma versus uveal melanoma

Ankit Singh Tomar, Anthony Fam, Paul T. Finger, Codrin E. Iacob

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Background: Ciliary body tumors can remain undetected and achieve large dimensions. Pigmented ciliary body tumors include: melanoma, leiomyoma and melanocytoma, however correct diagnosis may require tissue diagnosis with immunohistochemical stains. Case presentation: Two men presented with identical ciliochoroidal tumors. Both had darkly pigmented dome-shaped anterior uveal masses, exudative retinal detachments and transillumination shadowing. Ocular PET-CT imaging revealed that both were metabolically active consistent with a diagnosis of cancer. However, immunohistochemical examination revealed one a leiomyoma and the other melanoma. Conclusion: Uveal leiomyoma can be an indistinguishable doppelgänger to ciliochoroidal melanoma, where the diagnosis can only be established by immunohistopathology.

Original languageEnglish
Article number101040
JournalAmerican Journal of Ophthalmology Case Reports
Volume22
DOIs
StatePublished - Jun 2021
Externally publishedYes

Keywords

  • Benign
  • Immunohistochemistry
  • Leiomyoma
  • Melanoma
  • Uvea

Fingerprint

Dive into the research topics of 'Doppelgänger dilemma: Leiomyoma versus uveal melanoma'. Together they form a unique fingerprint.

Cite this