Dopaminergic modulation of emotional memory in Parkinson's disease

Thomas D. Hälbig; Ute A. Kopp; Franziska Wodarz; Joan C. Borod; Jean Michel Gracies; Georg Ebersbach; Andreas Kupsch

doi:10.1007/s00702-008-0061-4

Dopaminergic modulation of emotional memory in Parkinson's disease

Thomas D. Hälbig, Ute A. Kopp, Franziska Wodarz, Joan C. Borod, Jean Michel Gracies, Georg Ebersbach, Andreas Kupsch

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The aim of this study was to assess the effect of dopaminergic treatment on emotional memory in patients with Parkinson's disease (PD). We tested memory for emotional and neutral visual stimuli in ten non-demented PD patients on and off dopaminergic medication. Patients recalled significantly more emotional items during the off- than on-medication testing session. In contrast, treatment condition did not affect memory for neutral items. These findings demonstrate that emotional memory deficits observed in PD may result from dopaminergic treatment and suggest an involvement of dopaminergic neurotransmission in emotional processing.

Original language	English
Pages (from-to)	1159-1163
Number of pages	5
Journal	Journal of Neural Transmission
Volume	115
Issue number	8
DOIs	https://doi.org/10.1007/s00702-008-0061-4
State	Published - Aug 2008

Keywords

Basal ganglia
Dopamine
Emotional memory
Parkinson's disease

Access to Document

10.1007/s00702-008-0061-4

Cite this

@article{eb46cf80305a496191d3030e3c3a8c6f,

title = "Dopaminergic modulation of emotional memory in Parkinson's disease",

abstract = "The aim of this study was to assess the effect of dopaminergic treatment on emotional memory in patients with Parkinson's disease (PD). We tested memory for emotional and neutral visual stimuli in ten non-demented PD patients on and off dopaminergic medication. Patients recalled significantly more emotional items during the off- than on-medication testing session. In contrast, treatment condition did not affect memory for neutral items. These findings demonstrate that emotional memory deficits observed in PD may result from dopaminergic treatment and suggest an involvement of dopaminergic neurotransmission in emotional processing.",

keywords = "Basal ganglia, Dopamine, Emotional memory, Parkinson's disease",

author = "H{\"a}lbig, {Thomas D.} and Kopp, {Ute A.} and Franziska Wodarz and Borod, {Joan C.} and Gracies, {Jean Michel} and Georg Ebersbach and Andreas Kupsch",

year = "2008",

month = aug,

doi = "10.1007/s00702-008-0061-4",

language = "English",

volume = "115",

pages = "1159--1163",

journal = "Journal of Neural Transmission",

issn = "0300-9564",

publisher = "Springer",

number = "8",

}

TY - JOUR

T1 - Dopaminergic modulation of emotional memory in Parkinson's disease

AU - Hälbig, Thomas D.

AU - Kopp, Ute A.

AU - Wodarz, Franziska

AU - Borod, Joan C.

AU - Gracies, Jean Michel

AU - Ebersbach, Georg

AU - Kupsch, Andreas

PY - 2008/8

Y1 - 2008/8

N2 - The aim of this study was to assess the effect of dopaminergic treatment on emotional memory in patients with Parkinson's disease (PD). We tested memory for emotional and neutral visual stimuli in ten non-demented PD patients on and off dopaminergic medication. Patients recalled significantly more emotional items during the off- than on-medication testing session. In contrast, treatment condition did not affect memory for neutral items. These findings demonstrate that emotional memory deficits observed in PD may result from dopaminergic treatment and suggest an involvement of dopaminergic neurotransmission in emotional processing.

AB - The aim of this study was to assess the effect of dopaminergic treatment on emotional memory in patients with Parkinson's disease (PD). We tested memory for emotional and neutral visual stimuli in ten non-demented PD patients on and off dopaminergic medication. Patients recalled significantly more emotional items during the off- than on-medication testing session. In contrast, treatment condition did not affect memory for neutral items. These findings demonstrate that emotional memory deficits observed in PD may result from dopaminergic treatment and suggest an involvement of dopaminergic neurotransmission in emotional processing.

KW - Basal ganglia

KW - Dopamine

KW - Emotional memory

KW - Parkinson's disease

UR - http://www.scopus.com/inward/record.url?scp=49749124209&partnerID=8YFLogxK

U2 - 10.1007/s00702-008-0061-4

DO - 10.1007/s00702-008-0061-4

M3 - Article

C2 - 18506391

AN - SCOPUS:49749124209

SN - 0300-9564

VL - 115

SP - 1159

EP - 1163

JO - Journal of Neural Transmission

JF - Journal of Neural Transmission

IS - 8

ER -

Dopaminergic modulation of emotional memory in Parkinson's disease

Abstract

Keywords

Access to Document

Fingerprint

Cite this