Does medical therapy for thoracic aortic aneurysms really work? Are β-blockers truly indicated? CON

Steve L. Liao; Sammy Elmariah; Sarina van der Zee; Brett A. Sealove; Valentin Fuster

doi:10.1016/j.ccl.2010.01.002

Does medical therapy for thoracic aortic aneurysms really work? Are β-blockers truly indicated? CON

Steve L. Liao, Sammy Elmariah, Sarina van der Zee, Brett A. Sealove, Valentin Fuster

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

Thoracic aortic aneurysms (TAA) often represent the final manifestation of hereditary or degenerative disease processes. TAA are primarily caused by age-related degenerative changes. In this article, the authors highlight the most common pathophysiologic mechanisms responsible for TAA formation and review the paucity of evidence supporting the spectrum of medical therapies for TAA other than renin-angiotensin inhibition. More clinical trials on TAA are required before medical therapies such as β-blockers, statins, and macrolide antibiotics can be recommended.

Original language	English
Pages (from-to)	261-269
Number of pages	9
Journal	Cardiology Clinics
Volume	28
Issue number	2
DOIs	https://doi.org/10.1016/j.ccl.2010.01.002
State	Published - May 2010

Keywords

Aortic aneurysm
Medical therapy
β-Blockers

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10.1016/j.ccl.2010.01.002

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title = "Does medical therapy for thoracic aortic aneurysms really work? Are β-blockers truly indicated? CON",

abstract = "Thoracic aortic aneurysms (TAA) often represent the final manifestation of hereditary or degenerative disease processes. TAA are primarily caused by age-related degenerative changes. In this article, the authors highlight the most common pathophysiologic mechanisms responsible for TAA formation and review the paucity of evidence supporting the spectrum of medical therapies for TAA other than renin-angiotensin inhibition. More clinical trials on TAA are required before medical therapies such as β-blockers, statins, and macrolide antibiotics can be recommended.",

keywords = "Aortic aneurysm, Medical therapy, β-Blockers",

author = "Liao, {Steve L.} and Sammy Elmariah and {van der Zee}, Sarina and Sealove, {Brett A.} and Valentin Fuster",

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AU - Liao, Steve L.

AU - Elmariah, Sammy

AU - van der Zee, Sarina

AU - Sealove, Brett A.

AU - Fuster, Valentin

PY - 2010/5

Y1 - 2010/5

N2 - Thoracic aortic aneurysms (TAA) often represent the final manifestation of hereditary or degenerative disease processes. TAA are primarily caused by age-related degenerative changes. In this article, the authors highlight the most common pathophysiologic mechanisms responsible for TAA formation and review the paucity of evidence supporting the spectrum of medical therapies for TAA other than renin-angiotensin inhibition. More clinical trials on TAA are required before medical therapies such as β-blockers, statins, and macrolide antibiotics can be recommended.

AB - Thoracic aortic aneurysms (TAA) often represent the final manifestation of hereditary or degenerative disease processes. TAA are primarily caused by age-related degenerative changes. In this article, the authors highlight the most common pathophysiologic mechanisms responsible for TAA formation and review the paucity of evidence supporting the spectrum of medical therapies for TAA other than renin-angiotensin inhibition. More clinical trials on TAA are required before medical therapies such as β-blockers, statins, and macrolide antibiotics can be recommended.

KW - Aortic aneurysm

KW - Medical therapy

KW - β-Blockers

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JO - Cardiology Clinics

JF - Cardiology Clinics

IS - 2

ER -

Does medical therapy for thoracic aortic aneurysms really work? Are β-blockers truly indicated? CON

Abstract

Keywords

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