Does FASing Out New Fat in the Hypothalamus Make You Slim?

Christoph Buettner

Research output: Contribution to journalShort surveypeer-review

3 Scopus citations

Abstract

Fatty acid synthase (FAS) is a key enzyme for lipogenesis. A recent study (Chakravarthy et al., 2007) shows that the targeted deletion of FAS in hypothalamic neurons produces hypophagic, lean mice and suggests that PPARα signaling is an important mediator of the effects of FAS on energy homeostasis.

Original languageEnglish
Pages (from-to)249-251
Number of pages3
JournalCell Metabolism
Volume6
Issue number4
DOIs
StatePublished - 3 Oct 2007
Externally publishedYes

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