Abstract
The clinical management of venous ulcers is debatable; however, a better understanding of the physiology has led to development of new treatment modalities. At the authors' center, bilayered extracellular matrix (ECM) technology (OASIS® Wound Matrix, Healthpoint, Ltd., Fort Worth, Tex) has been used to treat various lower-extremity wounds. In this retrospective study, the authors attempted to determine if ECM with a classic Unna boot method of compression was more effective at healing venous stasis ulcers than traditional Unna compression dressing supplemented by a wound drainage controlling agent alone. Thirty-three randomized outpatients diagnosed with venous insufficiency and venous leg ulcers were recruited to the study. The patients were divided into 2 groups based on type of dressing applied. Group A was treated with the commercially available ECM and application of a classic Unna boot method of compression. Group B was treated with the classic Unna boot method. The complete healing rates were found to be 76.56% (13/18) in Group A and 74.46% (11/15) in Group B at the end of 12 weeks. The tri-weekly wound surface reduction (cm 2) was 2.78±0.32 for Group A and 2.34±0.21 for Group B. The comparison of both groups according to the complete healing rates showed no significant difference (p>0.05).
Original language | English |
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Pages (from-to) | 27-31 |
Number of pages | 5 |
Journal | Wounds |
Volume | 17 |
Issue number | 2 |
State | Published - Feb 2005 |
Externally published | Yes |