Documentation of recovery from vitamin A deficiency-related retinopathy via multimodal imaging and electroretinogram testing

Stephanie Choi, Saagar Pandit, Sachi A. Patil, Scott E. Brodie

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Purpose: To describe vitamin A deficiency using multimodal functional visual assessments and imaging. Methods/Case: A 50-year-old female with past medical history significant for Roux-en-Y gastric bypass surgery complained of nyctalopia and “yellowing” of vision. Results: Vitamin A levels were noted to be < 0.06 mg/L (normal 0.3–0.12 mg/L). Fundus examination was notable for peripheral yellow punctate lesions, superior arcuate defects on HVF 30–2 testing, an indistinct ellipsoid zone on SD-OCT, and absent rod responses and severely reduced amplitudes for the cone photoreceptors on full-field ERG. These findings resolved with initiation of parenteral vitamin A supplementation. Conclusion: This report documents an example of vitamin A deficiency in the developed world. We aim to provide a comprehensive description of clinical examination and multimodal imaging findings before and after vitamin supplementation for vitamin A deficiency.

Original languageEnglish
Pages (from-to)157-162
Number of pages6
JournalDocumenta Ophthalmologica
Volume145
Issue number2
DOIs
StatePublished - Oct 2022
Externally publishedYes

Keywords

  • Bariatric surgery
  • Electroretinography
  • Full-field ERG
  • Optical coherence tomography
  • Visual field
  • Vitamin A deficiency

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