TY - JOUR
T1 - Dobutamine stress echocardiography
T2 - Does it predict response to beta-blockers in patients with heart failure?
AU - Bangalore, Sripal
AU - Hematpour, Khashayar
AU - Chaudhry, Farooq A.
PY - 2006/6
Y1 - 2006/6
N2 - In patients with chronic heart failure (CHF), β-blockers have been shown to improve symptoms, exercise tolerance, functional capacity, quality of life, left ventricular ejection fraction (LVEF), and survival and reduce sudden cardiac death. However, the effect of β-blockers in patients with CHF has also been shown to be heterogeneous, with improved LVEF in some and worsening or no response in others. This review summarizes studies evaluating the role of inotropic contractile reserve (ICR) with dobutamine stress echocardiography in predicting responders to β-blocker therapy among patients with heart failure. It also reviews the rationale for the beneficial effects of ICR in this cohort.
AB - In patients with chronic heart failure (CHF), β-blockers have been shown to improve symptoms, exercise tolerance, functional capacity, quality of life, left ventricular ejection fraction (LVEF), and survival and reduce sudden cardiac death. However, the effect of β-blockers in patients with CHF has also been shown to be heterogeneous, with improved LVEF in some and worsening or no response in others. This review summarizes studies evaluating the role of inotropic contractile reserve (ICR) with dobutamine stress echocardiography in predicting responders to β-blocker therapy among patients with heart failure. It also reviews the rationale for the beneficial effects of ICR in this cohort.
UR - http://www.scopus.com/inward/record.url?scp=33750352932&partnerID=8YFLogxK
U2 - 10.1007/s11897-006-0008-8
DO - 10.1007/s11897-006-0008-8
M3 - Review article
C2 - 16933402
AN - SCOPUS:33750352932
SN - 1546-9530
VL - 3
SP - 96
EP - 102
JO - Current Heart Failure Reports
JF - Current Heart Failure Reports
IS - 2
ER -