@inbook{fb853619771b42d0a57cb7d8ad29a2ec,
title = "DNA vaccines: Experiences in the swine model",
abstract = "DNA vaccination is one of the most fascinating vaccine-strategies currently in development. Two of the main advantages of DNA immunization rely on its simplicity and fl exibility, being ideal to dissect both the immune mechanisms and the antigens involved in protection against a given pathogen. Here, we describe several strategies used to enhance the immune responses induced and the protection afforded by experimental DNA vaccines tested in swine and provide with very basic protocol describing the generation and in vivo application of a prototypic DNA vaccine. Only time will tell the last word regarding the definative implementation of DNA vaccination in the field.",
keywords = "APC, Antibodies, Antigen presentation, Cytotoxic T-cell responses (CTL), DNA vaccine, ELI, Electroporation, Genetic adjuvant, Swine, Veterinary virology",
author = "Francesc Accensi and Fernando Rodr{\'i}guez and Monteagudo, {Paula L.}",
note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2016.",
year = "2016",
doi = "10.1007/978-1-4939-3008-1_4",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "49--62",
booktitle = "Methods in Molecular Biology",
}