Divided café-au-lait macule of the mouth

Amanda Sergay, Nanette B. Silverberg

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


We describe a 4-year-old, otherwise healthy boy with a congenital history of a perioral and labial segmental café-au-lait macule, who was noted to have unilateral localized gingival hyperpigmentation that aligned with the café-au-lait macule. This case is highly illustrative of the embryologic timing of the genetic event locally, which leads to café-au-lait type hyperpigmentation. Because the facial features and the ectoderm overlying the facial muscles develop around the third to fourth week of gestation, the distribution of this café-au-lait macule suggests development at the same time.

Original languageEnglish
Pages (from-to)S98-S99
JournalJournal of the American Academy of Dermatology
Issue number5 SUPPL.
StatePublished - May 2007
Externally publishedYes


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