Distinctive neurons of the anterior cingulate and frontoinsular cortex: A historical perspective

William W. Seeley, Florian T. Merkle, Stephanie E. Gaus, A. D. Craig, John M. Allman, Patrick R. Hof

Research output: Contribution to journalReview articlepeer-review

70 Scopus citations

Abstract

Human anterior cingulate and frontoinsular cortices participate in healthy social-emotional processing. These regions feature 2 related layer 5 neuronal morphotypes, the von Economo neurons and fork cells. In this paper, we review the historical accounts of these neurons and provide a German-to-English translation of von Economo's seminal paper describing the neurons which have come to bear his name. We close with a brief discussion regarding the functional and clinical relevance of these neurons and their home regions.

Original languageEnglish
Pages (from-to)245-247
Number of pages3
JournalCerebral Cortex
Volume22
Issue number2
DOIs
StatePublished - Feb 2012

Keywords

  • Anterior cingulate cortex
  • Cytoarchitecture
  • Fork cell
  • Insula
  • Von Economo neuron

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