Distinct distributions of genomic features of the 5' and 3' partners of coding somatic cancer gene fusions: arising mechanisms and functional implications

Keyphrases

• 3-prime 10%
• 3′-untranslated Region (3′-UTR) 10%
• 5′-untranslated Region (5′-UTR) 10%
• Bilateria 10%
• Cancer Genes 100%
• Cancer Mechanisms 10%
• Composition Distribution 10%
• Content Bias 10%
• Encoded Protein 10%
• Evolutionary 10%
• Expression Breadth 10%
• Functional Consequences 100%
• Functional Level 10%
• Functional Types 10%
• Fusion Partner 30%
• GC Skew 20%
• Gene Age 10%
• Gene Expression 10%
• Gene Family 10%
• Gene Fusion 100%
• Gene Origin 10%
• Genomic Features 100%
• Human Cancer 10%
• Lagging Strand Replication 10%
• Leading Strand 10%
• Length Distribution 10%
• Level of Functioning 10%
• N-terminal Sequence 10%
• Nucleotide Content 10%
• Oncogene 10%
• Polarity Features 10%
• R-loop Formation 10%
• R-loops 10%
• Replication Origin 10%
• Sequence Features 10%
• Somatic Amplification 10%
• Somatic Cancers 100%
• Stratification Phenomenon 10%
• Structural Genomics 10%
• Targeted Therapeutics 10%
• Tumor Suppressor Gene 10%

Biochemistry, Genetics and Molecular Biology

• Bilateria 11%
• DNA RNA Hybridization 11%
• Evolution 11%
• Gene Expression 11%
• Gene Fusion 100%
• Genomics 100%
• Multigene Family 11%
• N-Terminus 11%
• Origin of Replication 11%
• Proto Oncogene 11%
• R-Loop 22%
• Somatosensory Amplification 11%
• Structural Genomics 11%
• Tumor Gene 100%
• Tumor Suppressor Gene 11%
• Untranslated Region 22%

Neuroscience

• Amino Terminal Sequence 9%
• Gene Expression 9%
• Gene Fusion 81%
• Multigene Family 9%
• Origin of Replication 9%
• Proto Oncogene 9%
• Somatics 100%
• Structural Genomics 9%
• Tumor Gene 100%
• Tumor Suppressor Gene 9%
• Untranslated Region 18%