Distamycin A-DAPI banding of nonfluorescent Y (Ynf) chromosomes in 45,X/46,XYnf mosaicism

Lawrence P. Wisniewski, Kurt Hirschhorn

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The distamycin A-DAPI banding patterns of nonfluorescent, nonheterochromatic Y chromosomes (Ynf) in two patients with 45,X/46,XYnf mosaicism were investigated. In both cases moderately fluorescent bands were observed near the centromere and on the distal long arm of the Ynf. These bands were similar to the centrometric band on normal Y chromosomes and support the hypothesis that the Ynf is an isodicentric chromosome derived from the proximal portion of the Y chromosome.

Original languageEnglish
Pages (from-to)130-132
Number of pages3
JournalHuman Genetics
Volume60
Issue number2
DOIs
StatePublished - Jun 1982

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