Disseminated community-acquired USA300 methicillin-resistant Staphylococcus aureus pyomyositis and septic pulmonary emboli in an immunocompetent adult

Joseph F. Woodward, Dhruba J. Sengupta, Brad T. Cookson, James O. Park, E. Patchen Dellinger

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Background: Recent reports have increasingly recognized methicillin-resistant Staphylococcus aureus (MRSA) as an important etiology of pyomyositis, an uncommon disease entity. Specific virulence factors such as the Panton-Valentine leukocidin protein have been identified that may play a role in the pathophysiology of pyomyositis, especially when community-acquired MRSA is implicated. Methods: We review a case of disseminated pyomyositis and septic pulmonary emboli in an immunocompetent adult in whom a pvl+ USA300 clone was isolated. Results: The degree of dissemination in this patient suggests an emerging level of virulence for community-acquired MRSA that has not been reported previously. Conclusion: The clinical history and management of severe disseminated pyomyositis, including diagnostic modalities, antimicrobial therapy, and surgical drainage, require an aggressive approach.

Original languageEnglish
Pages (from-to)59-63
Number of pages5
JournalSurgical Infections
Volume11
Issue number1
DOIs
StatePublished - 1 Feb 2010
Externally publishedYes

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