TY - JOUR
T1 - Dissecting neural mechanisms of prosocial behaviors
AU - Walsh, Jessica J.
AU - Christoffel, Daniel J.
AU - Wu, Xiaoting
AU - Pomrenze, Matthew B.
AU - Malenka, Robert C.
N1 - Publisher Copyright:
© 2020 Elsevier Ltd
PY - 2021/6
Y1 - 2021/6
N2 - Prosocial behaviors are essential for group cooperation, which enrich life experience and enhance survival. These complex behaviors are governed by intricate interactions between numerous neural circuits functioning in concert. Impairments in prosocial interactions result from disruptions of this coordinated brain activity and are a prominent feature of several pathological conditions including autism spectrum disorder, depression and addiction. Here we highlight recent studies that use advanced techniques to anatomically map, monitor and manipulate neural circuits that influence prosocial behavior. These recent findings provide important clues to unravel the complexities of the neural mechanisms that mediate prosocial interactions and offer insights into new strategies for the treatment of aberrant social behavior.
AB - Prosocial behaviors are essential for group cooperation, which enrich life experience and enhance survival. These complex behaviors are governed by intricate interactions between numerous neural circuits functioning in concert. Impairments in prosocial interactions result from disruptions of this coordinated brain activity and are a prominent feature of several pathological conditions including autism spectrum disorder, depression and addiction. Here we highlight recent studies that use advanced techniques to anatomically map, monitor and manipulate neural circuits that influence prosocial behavior. These recent findings provide important clues to unravel the complexities of the neural mechanisms that mediate prosocial interactions and offer insights into new strategies for the treatment of aberrant social behavior.
UR - http://www.scopus.com/inward/record.url?scp=85097067339&partnerID=8YFLogxK
U2 - 10.1016/j.conb.2020.11.006
DO - 10.1016/j.conb.2020.11.006
M3 - Review article
C2 - 33278639
AN - SCOPUS:85097067339
SN - 0959-4388
VL - 68
SP - 9
EP - 14
JO - Current Opinion in Neurobiology
JF - Current Opinion in Neurobiology
ER -