Skip to main navigation Skip to search Skip to main content

Disentangled and Proportional Representation Learning for Multi-view Brain Connectomes

  • Yanfu Zhang
  • , Liang Zhan
  • , Shandong Wu
  • , Paul Thompson
  • , Heng Huang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

5 Scopus citations

Abstract

Diffusion MRI-derived brain structural connectomes or brain networks are widely used in the brain research. However, constructing brain networks is highly dependent on various tractography algorithms, which leads to difficulties in deciding the optimal view concerning the downstream analysis. In this paper, we propose to learn a unified representation from multi-view brain networks. Particularly, we expect the learned representations to convey the information from different views fairly and in a disentangled sense. We achieve the disentanglement via an approach using unsupervised variational graph auto-encoders. We achieve the view-wise fairness, i.e. proportionality, via an alternative training routine. More specifically, we construct an analogy between training the deep network and the network flow problem. Based on the analogy, the fair representations learning is attained via a network scheduling algorithm aware of proportionality. The experimental results demonstrate that the learned representations fit various downstream tasks well. They also show that the proposed approach effectively preserves the proportionality.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2021 - 24th International Conference, Proceedings
EditorsMarleen de Bruijne, Philippe C. Cattin, Stéphane Cotin, Nicolas Padoy, Stefanie Speidel, Yefeng Zheng, Caroline Essert
PublisherSpringer Science and Business Media Deutschland GmbH
Pages508-518
Number of pages11
ISBN (Print)9783030872335
DOIs
StatePublished - 2021
Externally publishedYes
Event24th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2021 - Virtual, Online
Duration: 27 Sep 20211 Oct 2021

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume12907 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference24th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2021
CityVirtual, Online
Period27/09/211/10/21

Keywords

  • Alzheimer’s disease
  • Brain connectome
  • Multi-view
  • Prediction

Fingerprint

Dive into the research topics of 'Disentangled and Proportional Representation Learning for Multi-view Brain Connectomes'. Together they form a unique fingerprint.

Cite this