Discordant Cortisol Response in Pituitary Disease

Paul M. Copeland; Paul W. Ladenson; Kenneth L. Cohen; Richard D. Kayne; Jean François Delaloye; Fulgencio Gomez; Peter Buckhardt; George C. Borst; H. Jakob Michenfelder; John T. O'brian

doi:10.1056/NEJM198211043071919

Discordant Cortisol Response in Pituitary Disease

Paul M. Copeland, Paul W. Ladenson, Kenneth L. Cohen, Richard D. Kayne, Jean François Delaloye, Fulgencio Gomez, Peter Buckhardt, George C. Borst, H. Jakob Michenfelder, John T. O'brian

Research output: Contribution to journal › Letter › peer-review

4 Scopus citations

Abstract

To the Editor: Borst and his colleagues have elucidated the potential for underdiagnosis of secondary adrenal insufficiency arising from the use of the short ACTH test in patients with long-standing pituitary disease (June 17 issue).¹ We would add that this caution has special importance in the evaluation of patients immediately after pituitary surgery. Although the suggestion has been made that the results of the short ACTH test and those of the insulin-tolerance test correlate in this setting,² we have observed initially discordant cortisol responses to a short ACTH test and an insulin-tolerance test within a week of transsphenoidal surgery,.

Original language	English
Pages (from-to)	1217-1219
Number of pages	3
Journal	New England Journal of Medicine
Volume	307
Issue number	19
DOIs	https://doi.org/10.1056/NEJM198211043071919
State	Published - 4 Nov 1982
Externally published	Yes

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title = "Discordant Cortisol Response in Pituitary Disease",

abstract = "To the Editor: Borst and his colleagues have elucidated the potential for underdiagnosis of secondary adrenal insufficiency arising from the use of the short ACTH test in patients with long-standing pituitary disease (June 17 issue).1 We would add that this caution has special importance in the evaluation of patients immediately after pituitary surgery. Although the suggestion has been made that the results of the short ACTH test and those of the insulin-tolerance test correlate in this setting,2 we have observed initially discordant cortisol responses to a short ACTH test and an insulin-tolerance test within a week of transsphenoidal surgery,.",

author = "Copeland, {Paul M.} and Ladenson, {Paul W.} and Cohen, {Kenneth L.} and Kayne, {Richard D.} and Delaloye, {Jean Fran{\c c}ois} and Fulgencio Gomez and Peter Buckhardt and Borst, {George C.} and Michenfelder, {H. Jakob} and O'brian, {John T.}",

year = "1982",

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doi = "10.1056/NEJM198211043071919",

language = "English",

volume = "307",

pages = "1217--1219",

journal = "New England Journal of Medicine",

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TY - JOUR

T1 - Discordant Cortisol Response in Pituitary Disease

AU - Copeland, Paul M.

AU - Ladenson, Paul W.

AU - Cohen, Kenneth L.

AU - Kayne, Richard D.

AU - Delaloye, Jean François

AU - Gomez, Fulgencio

AU - Buckhardt, Peter

AU - Borst, George C.

AU - Michenfelder, H. Jakob

AU - O'brian, John T.

PY - 1982/11/4

Y1 - 1982/11/4

N2 - To the Editor: Borst and his colleagues have elucidated the potential for underdiagnosis of secondary adrenal insufficiency arising from the use of the short ACTH test in patients with long-standing pituitary disease (June 17 issue).1 We would add that this caution has special importance in the evaluation of patients immediately after pituitary surgery. Although the suggestion has been made that the results of the short ACTH test and those of the insulin-tolerance test correlate in this setting,2 we have observed initially discordant cortisol responses to a short ACTH test and an insulin-tolerance test within a week of transsphenoidal surgery,.

AB - To the Editor: Borst and his colleagues have elucidated the potential for underdiagnosis of secondary adrenal insufficiency arising from the use of the short ACTH test in patients with long-standing pituitary disease (June 17 issue).1 We would add that this caution has special importance in the evaluation of patients immediately after pituitary surgery. Although the suggestion has been made that the results of the short ACTH test and those of the insulin-tolerance test correlate in this setting,2 we have observed initially discordant cortisol responses to a short ACTH test and an insulin-tolerance test within a week of transsphenoidal surgery,.

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U2 - 10.1056/NEJM198211043071919

DO - 10.1056/NEJM198211043071919

M3 - Letter

C2 - 6289102

AN - SCOPUS:0020474978

SN - 0028-4793

VL - 307

SP - 1217

EP - 1219

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 19

ER -

Discordant Cortisol Response in Pituitary Disease

Abstract

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