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Differentiation and integration of machine learning feature vectors

  • Xinying Mu
  • , Ana B. Pavel
  • , Mark Kon

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

This paper presents a new approach to the production of feature maps for the improvement of classification in machine learning. The idea is based on a calculus of differentiation and integration of feature vectors, which can be viewed as functions on a metric space or network. Based on this we propose a novel network-based binary machine learning classifier. We illustrate our method using molecular networks alone to distinguish phenotypes, including cancer types and subtypes. We include feature sets derived from diseasespecific gene co-expression networks in different cancer data sets using The Cancer Genome Atlas (TCGA) along with other previously published studies. We also illustrate our network-based predictor on another data type, based on infrared spectroscopy of lung cancer tissue.

Original languageEnglish
Title of host publicationProceedings - 2016 15th IEEE International Conference on Machine Learning and Applications, ICMLA 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages611-616
Number of pages6
ISBN (Electronic)9781509061662
DOIs
StatePublished - 31 Jan 2017
Externally publishedYes
Event15th IEEE International Conference on Machine Learning and Applications, ICMLA 2016 - Anaheim, United States
Duration: 18 Dec 201620 Dec 2016

Publication series

NameProceedings - 2016 15th IEEE International Conference on Machine Learning and Applications, ICMLA 2016

Conference

Conference15th IEEE International Conference on Machine Learning and Applications, ICMLA 2016
Country/TerritoryUnited States
CityAnaheim
Period18/12/1620/12/16

Keywords

  • Cancer
  • Classification
  • Gene coexpression networks
  • Kernel method

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