Differential Subsampling with Cartesian Ordering–MRA for Classifying Residual Treated Aneurysms

P. Shahrouki, R. Gupta, P. Belani, A. Chien, A. H. Doshi, R. De Leacy, J. T. Fifi, J. Mocco, K. Nael

Research output: Contribution to journalArticlepeer-review


BACKGROUND AND PURPOSE: Differential Subsampling with Cartesian Ordering (DISCO), an ultrafast high-spatial-resolution head MRA, has been introduced. We aimed to determine the diagnostic performance of DISCO-MRA in grading residual aneurysm in comparison with TOF-MRA in patients with treated intracranial aneurysms. MATERIALS AND METHODS: Patients with endovascular treatment and having undergone DISCO-MRA, TOF-MRA, and DSA were included for review. The voxel size and acquisition time were 0.75 × 0.75 × 1 mm3/6 seconds for DISCO-MRA and 0.6 × 0.6 × 1 mm3/6 minutes for TOF-MRA. Residual aneurysms were determined using the Modified Raymond-Roy Classification on TOF-MRA and DISCO-MRA by 2 neuroradiologists independently and were compared against DSA as the reference standard. Statistical analysis was performed using the k statistic and the x 2 test. RESULTS: Sixty-eight treated intracranial aneurysms were included. The intermodality agreement was k = 0.82 (95% CI, 0.67–0.97) between DISCO and DSA and 0.44 (95% CI, 0.28–0.61) between TOF and DSA. Modified Raymond-Roy Classification scores matched DSA scores in 60/68 cases (88%; x 2 = 144.4, P, .001 for DISCO and 46/68 cases (68%; x 2 = 65.0, P, .001) for TOF. The diagnostic accuracy for the detection of aneurysm remnants was higher for DISCO (0.96; 95% CI, 0.88–0.99) than for TOF (0.79; 95% CI, 0.68–0.88). CONCLUSIONS: In patients with endovascularly treated intracranial aneurysms, DISCO-MRA provides superior diagnostic performance in comparison with TOF-MRA in delineating residual aneurysms in a fraction of the time.

Original languageEnglish
Pages (from-to)887-892
Number of pages6
JournalAmerican Journal of Neuroradiology
Issue number6
StatePublished - 1 Jun 2022


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