Abstract
The differential size distribution of atrial dense granules (ADGs) in spontaneously hypertensive rats (SHR) and two normotensive controls. Wistar and Wistar-Kyoto (WKY) rats, was investigated. The ADGs in SHR were smaller than those in Wistar rats. The ADGs of WKY rats were of intermediate size. It is possible that ADGs are more rapidly secreted in SHR compared with WKY and Wistar rats or that the smaller-diameter granules may contain more atriopeptinogen than the larger granules. The intermediate size of the ADGs in WKY suggests that the WKY variant is morphologically intermediate between the SHR and Wistar strains.
| Original language | English |
|---|---|
| Pages (from-to) | 331-335 |
| Number of pages | 5 |
| Journal | Cells Tissues Organs |
| Volume | 137 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1990 |
| Externally published | Yes |
Keywords
- Atrial dense grannies
- Experimental controls
- Granule size
- Peptide storage
- Spontaneously hypertensive rats
- Wistar rats
- Wistar-Kyoto rats