Abstract
The differential-display proteomic patterns of colon cancer in serum were studied by using surface-enhanced laser desorption ionization (ELDI)-TOF mass spectrometry. The molecular mass of the 8.9 kDa marker in the colon cancer patients and normals was determined to an accuracy of ∼0.1. Plasma samples were analyzed from 34 patients with confirmed colon cancer and 14 normal controls. Blood plasma from patients and controls were diluted with 10% acetonitrile in PBS containing 50 mM NaCl. The average differential expression of the intensities of the 8.9 kDa protein was ∼3-fold higher in colon cancer patients than in the controls.
Original language | English |
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Pages | 215-216 |
Number of pages | 2 |
State | Published - 2002 |
Event | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States Duration: 2 Jun 2002 → 6 Jun 2002 |
Conference
Conference | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics |
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Country/Territory | United States |
City | Orlando, FL |
Period | 2/06/02 → 6/06/02 |