Differential Diagnosis between Endogenous and Exogenous Insulin-Induced Refractory Hypoglycemia in a Nondiabetic Patient

William A. Bauman, Rosalyn S. Yalow, Rosalyn S. Yalow

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

THIS report describes a nondiabetic patient who had rectal adenocarcinoma and who suffered an episode of acute hypoglycemia while receiving intravenous fluids containing glucose. Workup of the case required determination of whether the hypoglycemia was associated with the malignant disease or with hyperinsulinism. If hyperinsulinism had been the causative factor, it could have been a consequence of augmented endogenous insulin secretion or accidental injection of insulin. Laboratory studies distinguished directly and definitively among these possibilities. We concluded that NPH insulin had been inadvertently injected. Case Report The patient was a 67-year-old man with adenocarcinoma of the rectum. After radiotherapy, he.

Original languageEnglish
Pages (from-to)198-199
Number of pages2
JournalNew England Journal of Medicine
Volume303
Issue number4
DOIs
StatePublished - 24 Jul 1980
Externally publishedYes

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