Differential antimicrobial susceptibilities of Granulicatella adiacens and Abiotrophia defectiva

Ammara Mushtaq; Kerryl E. Greenwood-Quaintance; Nicolynn C. Cole; Peggy C. Kohner; Sherry M. Ihde; Gregory J. Strand; Lance W. Harper; Abinash Virk; Robin Patel

doi:10.1128/AAC.00485-16

Differential antimicrobial susceptibilities of Granulicatella adiacens and Abiotrophia defectiva

Ammara Mushtaq, Kerryl E. Greenwood-Quaintance, Nicolynn C. Cole, Peggy C. Kohner, Sherry M. Ihde, Gregory J. Strand, Lance W. Harper, Abinash Virk, Robin Patel

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

MICs of 25 Abiotrophia defectiva and 109 Granulicatella adiacens isolates were determined by broth microdilution. Using CLSI breakpoints, the susceptibilities of A. defectiva and G. adiacens isolates were, respectively, 24% and 34% to penicillin, 92% and 22% to ceftriaxone, 48% and 3% to cefepime, 72% and 87% to meropenem, 92% and 10% to cefotaxime, 100% and 97% to levofloxacin, 92% and 80% to clindamycin, and 24% and 50% to erythromycin. All isolates were susceptible to vancomycin. In the penicillin-susceptible subgroup, all A. defectiva isolates were susceptible to ceftriaxone; however, 62% of G. adiacens isolates were ceftriaxone nonsusceptible.

Original language	English
Pages (from-to)	5036-5039
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	60
Issue number	8
DOIs	https://doi.org/10.1128/AAC.00485-16
State	Published - Aug 2016
Externally published	Yes

Access to Document

10.1128/AAC.00485-16

Cite this

@article{7dca6863d6fe4bf49f7ec3dae9681ad6,

title = "Differential antimicrobial susceptibilities of Granulicatella adiacens and Abiotrophia defectiva",

abstract = "MICs of 25 Abiotrophia defectiva and 109 Granulicatella adiacens isolates were determined by broth microdilution. Using CLSI breakpoints, the susceptibilities of A. defectiva and G. adiacens isolates were, respectively, 24% and 34% to penicillin, 92% and 22% to ceftriaxone, 48% and 3% to cefepime, 72% and 87% to meropenem, 92% and 10% to cefotaxime, 100% and 97% to levofloxacin, 92% and 80% to clindamycin, and 24% and 50% to erythromycin. All isolates were susceptible to vancomycin. In the penicillin-susceptible subgroup, all A. defectiva isolates were susceptible to ceftriaxone; however, 62% of G. adiacens isolates were ceftriaxone nonsusceptible.",

author = "Ammara Mushtaq and Greenwood-Quaintance, {Kerryl E.} and Cole, {Nicolynn C.} and Kohner, {Peggy C.} and Ihde, {Sherry M.} and Strand, {Gregory J.} and Harper, {Lance W.} and Abinash Virk and Robin Patel",

year = "2016",

month = aug,

doi = "10.1128/AAC.00485-16",

language = "English",

volume = "60",

pages = "5036--5039",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "8",

}

TY - JOUR

T1 - Differential antimicrobial susceptibilities of Granulicatella adiacens and Abiotrophia defectiva

AU - Mushtaq, Ammara

AU - Greenwood-Quaintance, Kerryl E.

AU - Cole, Nicolynn C.

AU - Kohner, Peggy C.

AU - Ihde, Sherry M.

AU - Strand, Gregory J.

AU - Harper, Lance W.

AU - Virk, Abinash

AU - Patel, Robin

PY - 2016/8

Y1 - 2016/8

N2 - MICs of 25 Abiotrophia defectiva and 109 Granulicatella adiacens isolates were determined by broth microdilution. Using CLSI breakpoints, the susceptibilities of A. defectiva and G. adiacens isolates were, respectively, 24% and 34% to penicillin, 92% and 22% to ceftriaxone, 48% and 3% to cefepime, 72% and 87% to meropenem, 92% and 10% to cefotaxime, 100% and 97% to levofloxacin, 92% and 80% to clindamycin, and 24% and 50% to erythromycin. All isolates were susceptible to vancomycin. In the penicillin-susceptible subgroup, all A. defectiva isolates were susceptible to ceftriaxone; however, 62% of G. adiacens isolates were ceftriaxone nonsusceptible.

AB - MICs of 25 Abiotrophia defectiva and 109 Granulicatella adiacens isolates were determined by broth microdilution. Using CLSI breakpoints, the susceptibilities of A. defectiva and G. adiacens isolates were, respectively, 24% and 34% to penicillin, 92% and 22% to ceftriaxone, 48% and 3% to cefepime, 72% and 87% to meropenem, 92% and 10% to cefotaxime, 100% and 97% to levofloxacin, 92% and 80% to clindamycin, and 24% and 50% to erythromycin. All isolates were susceptible to vancomycin. In the penicillin-susceptible subgroup, all A. defectiva isolates were susceptible to ceftriaxone; however, 62% of G. adiacens isolates were ceftriaxone nonsusceptible.

UR - http://www.scopus.com/inward/record.url?scp=84979224999&partnerID=8YFLogxK

U2 - 10.1128/AAC.00485-16

DO - 10.1128/AAC.00485-16

M3 - Article

C2 - 27216060

AN - SCOPUS:84979224999

SN - 0066-4804

VL - 60

SP - 5036

EP - 5039

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 8

ER -

Differential antimicrobial susceptibilities of Granulicatella adiacens and Abiotrophia defectiva

Abstract

Access to Document

Fingerprint

Cite this