Difference in antibody induced redistribution of membrane IgM in EBV-genome free and EBV positive human lymphoid cells

E. Yefenof; G. Klein

doi:10.1016/0014-4827(76)90693-5

Difference in antibody induced redistribution of membrane IgM in EBV-genome free and EBV positive human lymphoid cells

E. Yefenof, G. Klein

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Antibody induced redistribution and capping of membrane-associated IgM was reduced in EBV-genome positive human lymphoid lines, compared to EBV-negative established lines. Superinfection of two EBV-negative lines with EBV has lead to permanent conversion into EBV-genome positive sublines. Surface IgM capping was reduced in parallel. In vitro EBV converted sublines thus resembled the originally EBV-positive lines with regard to their capping pattern and were clearly different from their EBV-negative parents.

Original language	English
Pages (from-to)	175-178
Number of pages	4
Journal	Experimental Cell Research
Volume	99
Issue number	1
DOIs	https://doi.org/10.1016/0014-4827(76)90693-5
State	Published - Apr 1976
Externally published	Yes

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title = "Difference in antibody induced redistribution of membrane IgM in EBV-genome free and EBV positive human lymphoid cells",

abstract = "Antibody induced redistribution and capping of membrane-associated IgM was reduced in EBV-genome positive human lymphoid lines, compared to EBV-negative established lines. Superinfection of two EBV-negative lines with EBV has lead to permanent conversion into EBV-genome positive sublines. Surface IgM capping was reduced in parallel. In vitro EBV converted sublines thus resembled the originally EBV-positive lines with regard to their capping pattern and were clearly different from their EBV-negative parents.",

author = "E. Yefenof and G. Klein",

note = "Funding Information: This work was supported by USPHS Contract NIH- Funding Information: This work was supported by Contract No. NOI CP 33316 within the Virus Cancer Program of the NCi. by Swedish Cancer Society, Lotten Bohman{\textquoteright}s Foundation and the King Gustaf V Jubilee Fund.",

year = "1976",

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doi = "10.1016/0014-4827(76)90693-5",

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journal = "Experimental Cell Research",

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T1 - Difference in antibody induced redistribution of membrane IgM in EBV-genome free and EBV positive human lymphoid cells

AU - Yefenof, E.

AU - Klein, G.

N1 - Funding Information: This work was supported by USPHS Contract NIH- Funding Information: This work was supported by Contract No. NOI CP 33316 within the Virus Cancer Program of the NCi. by Swedish Cancer Society, Lotten Bohman’s Foundation and the King Gustaf V Jubilee Fund.

PY - 1976/4

Y1 - 1976/4

N2 - Antibody induced redistribution and capping of membrane-associated IgM was reduced in EBV-genome positive human lymphoid lines, compared to EBV-negative established lines. Superinfection of two EBV-negative lines with EBV has lead to permanent conversion into EBV-genome positive sublines. Surface IgM capping was reduced in parallel. In vitro EBV converted sublines thus resembled the originally EBV-positive lines with regard to their capping pattern and were clearly different from their EBV-negative parents.

AB - Antibody induced redistribution and capping of membrane-associated IgM was reduced in EBV-genome positive human lymphoid lines, compared to EBV-negative established lines. Superinfection of two EBV-negative lines with EBV has lead to permanent conversion into EBV-genome positive sublines. Surface IgM capping was reduced in parallel. In vitro EBV converted sublines thus resembled the originally EBV-positive lines with regard to their capping pattern and were clearly different from their EBV-negative parents.

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Difference in antibody induced redistribution of membrane IgM in EBV-genome free and EBV positive human lymphoid cells

Abstract

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