Diamminodichloroplatinum in the chemotherapy of testicular tumors

D. J. Higby; H. J. Wallace; D. Albert; J. F. Holland

doi:10.1016/S0022-5347(17)59652-4

Diamminodichloroplatinum in the chemotherapy of testicular tumors

D. J. Higby, H. J. Wallace, D. Albert, J. F. Holland

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Abstract

Diamminodichloroplatinum, a new antitumor agent, was evaluated in 3 schedules during phases I and II trials. Fifteen patients with testicular tumors of various histologic types were treated. There were 7 complete remissions and tumor regressions occurred in 13 patients. Major toxicity was renal and gastrointestinal. There was little hematologic toxicity. The drug may have use in combination therapy with more myelosuppressive agents.

Original language	English
Pages (from-to)	100-104
Number of pages	5
Journal	Journal of Urology
Volume	112
Issue number	1
DOIs	https://doi.org/10.1016/S0022-5347(17)59652-4
State	Published - 1974
Externally published	Yes

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title = "Diamminodichloroplatinum in the chemotherapy of testicular tumors",

abstract = "Diamminodichloroplatinum, a new antitumor agent, was evaluated in 3 schedules during phases I and II trials. Fifteen patients with testicular tumors of various histologic types were treated. There were 7 complete remissions and tumor regressions occurred in 13 patients. Major toxicity was renal and gastrointestinal. There was little hematologic toxicity. The drug may have use in combination therapy with more myelosuppressive agents.",

author = "Higby, {D. J.} and Wallace, {H. J.} and D. Albert and Holland, {J. F.}",

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AU - Wallace, H. J.

AU - Albert, D.

AU - Holland, J. F.

PY - 1974

Y1 - 1974

N2 - Diamminodichloroplatinum, a new antitumor agent, was evaluated in 3 schedules during phases I and II trials. Fifteen patients with testicular tumors of various histologic types were treated. There were 7 complete remissions and tumor regressions occurred in 13 patients. Major toxicity was renal and gastrointestinal. There was little hematologic toxicity. The drug may have use in combination therapy with more myelosuppressive agents.

AB - Diamminodichloroplatinum, a new antitumor agent, was evaluated in 3 schedules during phases I and II trials. Fifteen patients with testicular tumors of various histologic types were treated. There were 7 complete remissions and tumor regressions occurred in 13 patients. Major toxicity was renal and gastrointestinal. There was little hematologic toxicity. The drug may have use in combination therapy with more myelosuppressive agents.

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C2 - 4858106

AN - SCOPUS:0016213447

SN - 0022-5347

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JO - Journal of Urology

JF - Journal of Urology

IS - 1

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Diamminodichloroplatinum in the chemotherapy of testicular tumors

Abstract

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