Diamminodichloroplatinum in the chemotherapy of testicular tumors

D. J. Higby, H. J. Wallace, D. Albert, J. F. Holland

Research output: Contribution to journalArticlepeer-review

113 Scopus citations


Diamminodichloroplatinum, a new antitumor agent, was evaluated in 3 schedules during phases I and II trials. Fifteen patients with testicular tumors of various histologic types were treated. There were 7 complete remissions and tumor regressions occurred in 13 patients. Major toxicity was renal and gastrointestinal. There was little hematologic toxicity. The drug may have use in combination therapy with more myelosuppressive agents.

Original languageEnglish
Pages (from-to)100-104
Number of pages5
JournalJournal of Urology
Issue number1
StatePublished - 1974
Externally publishedYes


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