Abstract
Objective: To assess the diagnostic value of 18F-FDG PET/CT combined with breath-hold spiral CT in pulmonary nodules. Methods: One hundred and fifty-four patients with 171 pulmonary nodules (≤3 cm) were studied. Each patient underwent 18F-FDG PET/CT (16 slices) examination during mild respiration and breath-hold spiral CT scan, while 123 patients underwent dual-time-point PET/CT examination. The diagnostic efficacy of 18F-FDG PET/CT combined with breath-hold spiral CT, 18F-FDG PET/CT, breath-hold spiral CT and taking SUV max≥2.50 as the threshold value for malignancy were compared. All results were proved by pathologically, or by diagnostic therapy or by clinical follow-up. Results: The SUV max routine was 4.51±3.06 in 118 malignant nodules, and 2.07±1.30 in 53 benign nodules. The sensitivity, specificity, accuracy and Youden' index of 18F-FDG PET/CT combined with breath-hold spiral CT was 95.80%, 81.10%, 91.20%and 0.77, respectively, higher than those of other three methods. Conclusion: 18F-FDG PET/CT combined with breath-hold spiral CT has high diagnostic value in the differentiation of pulmonary nodules.
| Original language | English |
|---|---|
| Pages (from-to) | 18-21 |
| Number of pages | 4 |
| Journal | Chinese Journal of Medical Imaging Technology |
| Volume | 26 |
| Issue number | 1 |
| State | Published - Jan 2010 |
| Externally published | Yes |
Keywords
- Diagnosis, differential
- Fluorodeoxyglucose F18
- Lung neoplasms
- Neoplasm staging
- Standardized uptake value
- Tomography, X-ray computed
- Tomography, emission-computed