Diagnostic Value of Myocardial Radionuclide Imaging in Patients with Multivessel Coronary Disease

Maria Eduarda Menezes de Siqueira, Erly Medeiros Vieira Segundo Neto, Juliana Fernandes Kelendjian, Paola Emanuela Pogio Smanio

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background: Myocardial perfusion radionuclide imaging (MPRI) is a noninvasive method extremely useful for evaluating ischemia in patients with coronary disease. However, the idea that this method would not be effective for patients with multivessel coronary disease is still entertained. Objective: Assess the v\alue of MPRI with gated-SPECT for tracing pharmacological stress-induced ischemia in patients with multivessel obstructive coronary disease. Methods: We evaluated 68 patients with multivessel obstructive coronary disease applying coronary angiography for performing MPRI under pharmacologic stress with dipyridamole. The tests were analyzed by two nuclear medicine physicians without prior knowledge of the result of the coronary angiography. Results: Gated-SPECT revealed that, out of the patients, 64 (92.8%) showed images of perfusion abnormalities and 4 (7.2%) showed normal perfusion, given that three of the latter showed functional changes. Conclusion: MPRI has shown high value for identifying patients with multivessel coronary disease, since most patients had perfusion abnormalities indicative of ischemia.

Original languageEnglish
Pages (from-to)194-198
Number of pages5
JournalArquivos Brasileiros de Cardiologia
Issue number3
StatePublished - Sep 2011
Externally publishedYes


  • Coronary artery disease/radionuclide imaging
  • Dipyridamole
  • Myocardial reperfusion
  • Radionuclide imaging/diagnostic use


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