Diagnosis of herpesvirus infections: Correlation of tzanck preparations with viral isolation

Mary R. Motyl, Edward J. Bottone, J. Michael Janda

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Evaluation of Giemsa-stained smears of scrapings from the base of vesicles or ulcers (Tzanck preparation) for the presence of multinucleated giant cells and/or intracellular inclusions were diagnostic for herpesvirus in 18 of 21 cases (86%) of culturally proved herpesvirus infections. Smears from four patients with varicella-zoster infection also revealed cytologic alterations characteristic of herpesvirus.

Original languageEnglish
Pages (from-to)157-160
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Volume2
Issue number2
DOIs
StatePublished - Apr 1984

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