Diagnosis of Food Allergy

Malika Gupta, Amanda Cox, Anna Nowak-Węgrzyn, Julie Wang

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations

Abstract

Food allergy diagnosis remains challenging. Most standard methods are unable to differentiate sensitization from clinical allergy. Recognizing food allergy is of utmost importance to prevent life-threatening reactions. On the other hand, faulty interpretation of tests leads to overdiagnosis and unnecessary food avoidances. Highly predictive models have been established for major food allergens based on skin prick testing and food-specific immunoglobulin E but are lacking for most other foods. Although many newer diagnostic techniques are improving the accuracy of food allergy diagnostics, an oral food challenge remains the only definitive method of confirming a food allergy.

Original languageEnglish
Pages (from-to)39-52
Number of pages14
JournalImmunology and Allergy Clinics of North America
Volume38
Issue number1
DOIs
StatePublished - Feb 2018

Keywords

  • Basophil activation test
  • Component-resolved diagnostic testing
  • Diagnosis
  • Epitope binding
  • Food allergy
  • Molecular allergen analysis
  • Serum-specific IgE
  • Skin prick test

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