TY - JOUR
T1 - Diagnosis, neurobiology, and treatment of pathological gambling
AU - DeCaria, Concetta M.
AU - Hollander, Eric
AU - Grossman, Robert
AU - Wong, Cheryl M.
AU - Mosovich, Serge A.
AU - Cherkasky, Scott
PY - 1996
Y1 - 1996
N2 - Pathological gambling is a disabling disorder that affects at least 2 1/4 million Americans and their families. Although pathological gambling has been characterized as an impulse control disorder, it has also been associated with compulsivity. Essential features of pathological gambling include constantly recurring gambling behavior that is maladaptive, in that personal, familial, and/or vocational endeavors are disrupted. Affective disorders and substance abuse often co-occur. Incidence of suicidality is extremely high. Despite the fact that this disorder is a widespread public health problem, few controlled studies of causes or treatment have been conducted. Preliminary neurobiological studies implicate serotonergic dysfunction in pathological gamblers. Treatment with serotonin reuptake inhibitors, such as clomipramine and fluvoxamine, may he effective in treating this disorder. Well-defined and controlled clinical trials in large samples of pathological gamblers are needed.
AB - Pathological gambling is a disabling disorder that affects at least 2 1/4 million Americans and their families. Although pathological gambling has been characterized as an impulse control disorder, it has also been associated with compulsivity. Essential features of pathological gambling include constantly recurring gambling behavior that is maladaptive, in that personal, familial, and/or vocational endeavors are disrupted. Affective disorders and substance abuse often co-occur. Incidence of suicidality is extremely high. Despite the fact that this disorder is a widespread public health problem, few controlled studies of causes or treatment have been conducted. Preliminary neurobiological studies implicate serotonergic dysfunction in pathological gamblers. Treatment with serotonin reuptake inhibitors, such as clomipramine and fluvoxamine, may he effective in treating this disorder. Well-defined and controlled clinical trials in large samples of pathological gamblers are needed.
UR - http://www.scopus.com/inward/record.url?scp=0029787452&partnerID=8YFLogxK
M3 - Review article
C2 - 8698687
AN - SCOPUS:0029787452
SN - 0160-6689
VL - 57
SP - 80
EP - 84
JO - Journal of Clinical Psychiatry
JF - Journal of Clinical Psychiatry
IS - SUPPL. 8
ER -